Triptans

Treatment for migraines accounts for $3.5 billion dollars worldwide. Triptans (almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan) are the leading class of medications used for this purpose on the global market.1 However, the increasing use of anticonvulsants and antidepressants for migraine prevention will in all probability continue to cut into the triptan market share. Triptans are available in tablet form to be taken by mouth, as nasal sprays and injections and area available only by prescription.

Side effects of triptans are often short lived. However you should contact your physician if side effects are severe or do not go away. Possible side effects include:

• flushing, tingling feeling
• feeling of warmth or heaviness
• drowsiness, dizziness
• upset stomach, diarrhea, vomiting
• irritation of the nose
• muscle cramps

If you experience any of the following symptoms, call your doctor immediately:

• pain or tightness in chest or throat
• sudden or severe stomach pain
• fast heartbeat
• difficulty breathing, wheezing
• redness, swelling, or itching of the eyelids, face, or lips
• skin rash, lumps, or hives
• change in vision

Drug Interactions - Triptans should not be used in patients with heart disease, blood vessel disease or severe liver disease. They also have a number of drug interactions including: other migraine medications, antidepressants, pain killers and many more. It is important to give your doctor and pharmacists a list of all the medications you are taking (over-the-counter and on prescription) before taking a triptan.